BV-2 Microglia

Authors

Affiliations

Nate Yomogida, PT, DPT

Doctor of Physical Therapy

B.S. in Kinesiology

Chloë Kerstein, PT, DPT

Doctor of Physical Therapy

B.A. in Neuroscience

BV-2 microglial cell line was derived from the immortalized murine neonatal microglia¹. BV-2 Microglial cells are used frequently by in vitro models in order to study brain inflammation as a substitute for the primary microglia¹. BV-2 Microglial cells are preferentially used for studies compared to primary microglia, due to the high fidelity of the BV-2 response¹.

References

1.

Weis GCC, Assmann CE, Mostardeiro VB, et al. Chlorpyrifos pesticide promotes oxidative stress and increases inflammatory states in BV-2 microglial cells: A role in neuroinflammation. Chemosphere. 2021;278:130417. doi:10.1016/j.chemosphere.2021.130417